Chemical constituents from stem bark and roots of Clausena anisata.
نویسندگان
چکیده
Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).
منابع مشابه
In vitro antibacterial and antibiotic-potentiation activities of the methanol extracts from Beilschmiedia acuta, Clausena anisata, Newbouldia laevis and Polyscias fulva against multidrug-resistant Gram-negative bacteria.
BACKGROUND The present study was designed to investigate the antibacterial activities of the methanol extracts from different parts of Beilschmedia acuta Kosterm (Lauraceae), Clausena anisata (Willd) Hook (Rutaceae), Newbouldia laevis Seem (Bignoniaceae) and Polyscias fulva (Hiern) Harms (Araliaceae) as well as their synergistic effects with antibiotics against a panel of Gram-negative bacteria...
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Anti-inflammatory and antipyretic activities of leaf extract of Clausena anisata were evaluated to ascertain the folkloric claim of its anti-inflammatory and antipyretic effects. The crude leaf extract (39–117mg/kg) of C. anisata was investigated for anti-inflammatory and antipyretic activities using various experimental models. The extract caused a significant (p<0.05–0.001) dose-dependent red...
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ETHNOPHARMACOLOGICAL RELEVANCE The leaves of Clausena anisata are used traditionally to expel maggots from wounds of animals in Zimbabwe. We have previously proved in the laboratory that the plant certainly affects the behaviour and growth of blowfly larvae. The objective of this study was to isolate and identify the active compounds responsible for this activity. MATERIALS AND METHODS The ac...
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ورودعنوان ژورنال:
- Molecules
دوره 17 11 شماره
صفحات -
تاریخ انتشار 2012